HIMA: High-Dimensional Mediation Analysis

Allows to estimate and test high-dimensional mediation effects based on advanced mediator screening and penalized regression techniques. Methods used in the package refer to Zhang H, Zheng Y, Zhang Z, Gao T, Joyce B, Yoon G, Zhang W, Schwartz J, Just A, Colicino E, Vokonas P, Zhao L, Lv J, Baccarelli A, Hou L, Liu L. Estimating and Testing High-dimensional Mediation Effects in Epigenetic Studies. Bioinformatics. (2016) <doi:10.1093/bioinformatics/btw351>. PMID: 27357171.

Version: 2.0.1
Depends: R (≥ 3.4.0), ncvreg, glmnet
Imports: utils, stats, MASS, survival, HDMT, hommel, iterators, parallel, foreach, doParallel
Published: 2022-07-18
Author: Yinan Zheng [aut, cre], Haixiang Zhang [aut], Lifang Hou [aut], Lei Liu [aut, cph]
Maintainer: Yinan Zheng <y-zheng at northwestern.edu>
BugReports: https://github.com/YinanZheng/HIMA/issues/
License: GPL-3
URL: https://github.com/YinanZheng/HIMA/
NeedsCompilation: no
Citation: HIMA citation info
Materials: README NEWS
In views: Epidemiology
CRAN checks: HIMA results

Documentation:

Reference manual: HIMA.pdf

Downloads:

Package source: HIMA_2.0.1.tar.gz
Windows binaries: r-devel: HIMA_2.0.1.zip, r-release: HIMA_2.0.1.zip, r-oldrel: HIMA_2.0.1.zip
macOS binaries: r-release (arm64): HIMA_2.0.1.tgz, r-oldrel (arm64): HIMA_2.0.1.tgz, r-release (x86_64): HIMA_2.0.1.tgz, r-oldrel (x86_64): HIMA_2.0.1.tgz
Old sources: HIMA archive

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