MBNMAtime: Run Time-Course Model-Based Network Meta-Analysis (MBNMA) Models

Fits Bayesian time-course models for model-based network meta-analysis (MBNMA) that allows inclusion of multiple time-points from studies. Repeated measures over time are accounted for within studies by applying different time-course functions, following the method of Pedder et al. (2019) <doi:10.1002/jrsm.1351>. The method allows synthesis of studies with multiple follow-up measurements that can account for time-course for a single or multiple treatment comparisons. Several general time-course functions are provided; others may be added by the user. Various characteristics can be flexibly added to the models, such as correlation between time points and shared class effects. The consistency of direct and indirect evidence in the network can be assessed using unrelated mean effects models and/or by node-splitting.

Version: 0.2.1
Depends: R (≥ 3.5.0)
Imports: knitr, grDevices, stats, graphics, utils, dplyr (≥ 0.7.4), R2jags (≥ 0.5-7), rjags (≥ 4-8), reshape2 (≥ 1.4.3), magrittr (≥ 1.5), checkmate (≥ 1.8.5), Rdpack (≥ 0.10-1)
Suggests: scales (≥ 1.0.0), overlapping (≥ 1.5.0), ggplot2 (≥ 2.2.1), ggdist (≥ 2.4.0), igraph (≥ 1.1.2), rgeos (≥ 0.5-2), crayon (≥ 1.3.4), splines (≥ 4.0.2), Hmisc (≥ 4.4-1), lspline (≥ 1.0-0), rmarkdown, zoo (≥ 1.8-8), testthat (≥ 1.0.2), RColorBrewer (≥ 1.1-2), mcmcplots (≥ 0.4.3)
Published: 2021-09-13
Author: Hugo Pedder [aut, cre], Nicky Welton [ctb, rev], Sofia Dias [ctb, rev], Meg Bennetts [ctb, rev], Martin Boucher [ctb, rev]
Maintainer: Hugo Pedder <hugopedder at gmail.com>
License: GPL-3
NeedsCompilation: no
SystemRequirements: JAGS (>= 4.3.0) (http://mcmc-jags.sourceforge.net)
Language: en-GB
Citation: MBNMAtime citation info
Materials: README NEWS
In views: MetaAnalysis
CRAN checks: MBNMAtime results

Documentation:

Reference manual: MBNMAtime.pdf
Vignettes: MBNMAtime for time-course Model-Based (Network) Meta-Analysis

Downloads:

Package source: MBNMAtime_0.2.1.tar.gz
Windows binaries: r-devel: MBNMAtime_0.2.1.zip, r-release: MBNMAtime_0.2.1.zip, r-oldrel: MBNMAtime_0.2.1.zip
macOS binaries: r-release (arm64): MBNMAtime_0.2.1.tgz, r-oldrel (arm64): MBNMAtime_0.2.1.tgz, r-release (x86_64): MBNMAtime_0.2.1.tgz, r-oldrel (x86_64): MBNMAtime_0.2.1.tgz
Old sources: MBNMAtime archive

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