PFIM: Population Fisher Information Matrix
Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>, Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>, Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>, Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>, Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.
| Version: | 5.0 |
| Depends: | R (≥ 4.0.0) |
| Imports: | methods, rmarkdown, stats, scales, deSolve, kableExtra, gtable, Deriv, grid, knitr, markdown, Matrix, ggplot2, ggbreak, pracma, Rcpp, filesstrings |
| Suggests: | testthat, inline, utils, devtools, htmltools |
| Published: | 2022-06-24 |
| Author: | France Mentré 
[aut],
Hervé Le Nagard [aut],
Romain Leroux [aut, cre],
Jérémy Seurat [aut],
Tran Bach Nguyen [ctb],
Caroline Bazzoli [ctb],
Emmanuelle Comets [ctb],
Anne Dubois [ctb],
Cyrielle Dumont [ctb],
Giulia Lestini [ctb],
Thi Huyen Tram Nguyen [ctb],
Thu Thuy Nguyen [ctb],
Sylvie Retout [ctb] |
| Maintainer: | Romain Leroux <romain.leroux at inserm.fr> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | PFIM results |
Documentation:
| Reference manual: | PFIM.pdf |
| Vignettes: |
Design evaluation and optimization 01 Design evaluation and optimization 02 Library of models |
Downloads:
| Package source: | PFIM_5.0.tar.gz |
| Windows binaries: | r-devel: PFIM_5.0.zip, r-release: PFIM_5.0.zip, r-oldrel: PFIM_5.0.zip |
| macOS binaries: | r-release (arm64): PFIM_5.0.tgz, r-oldrel (arm64): PFIM_5.0.tgz, r-release (x86_64): PFIM_5.0.tgz, r-oldrel (x86_64): PFIM_5.0.tgz |
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