SKAT: SNP-Set (Sequence) Kernel Association Test
Functions for kernel-regression-based association tests including Burden test, SKAT and SKAT-O. These methods aggregate individual SNP score statistics in a SNP set and efficiently compute SNP-set level p-values. Methods available in this package include SKAT described in Micheal Wu, Seunggeun Lee et al. (2011) <doi:10.1016/j.ajhg.2011.05.029>, SKAT-O in Seunggeun Lee et al. (2012) <doi:10.1093/biostatistics/kxs014>, combined test of rare and common variants in Iuliana Ionita-Laza and Seunggeun Lee et al. (2013) <doi:10.1016/j.ajhg.2013.04.015>, efficient resampling for binary traits in Seunggeun Lee et al. (2016) <doi:10.1093/biostatistics/kxv033>, and robust test for binary traits in Zhangchen Zhao et al. (2020) <doi:10.1016/j.ajhg.2019.11.012>.
| Version: |
2.2.4 |
| Depends: |
R (≥ 2.13.0), Matrix, SPAtest, RSpectra |
| Published: |
2022-03-29 |
| Author: |
Seunggeun (Shawn) Lee [aut, cre, cph],
Zhangchen Zhao [aut],
Larisa Miropolsky [aut],
Michael Wu [aut] |
| Maintainer: |
Seunggeun (Shawn) Lee <lee7801 at snu.ac.kr> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: |
yes |
| CRAN checks: |
SKAT results |
Documentation:
Downloads:
Reverse dependencies:
| Reverse depends: |
FSTpackage, GenoScan, LGEWIS, LGRF, Mega2R, WGScan |
| Reverse imports: |
GBJ, MetaSKAT, SMUT, zfa |
| Reverse suggests: |
BGData, bigQF, FastKM, seqminer |
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