pmxTools: Pharmacometric and Pharmacokinetic Toolkit

Pharmacometric tools for common data analytical tasks; closed-form solutions for calculating concentrations at given times after dosing based on compartmental PK models (1-compartment, 2-compartment and 3-compartment, covering infusions, zero- and first-order absorption, and lag times, after single doses and at steady state, per Bertrand & Mentre (2008) <http://lixoft.com/wp-content/uploads/2016/03/PKPDlibrary.pdf>); parametric simulation from NONMEM-generated parameter estimates and other output; and parsing, tabulating and plotting results generated by Perl-speaks-NONMEM (PsN).

Version: 1.2.3
Depends: MASS, stringr, magrittr, data.tree, DiagrammeR
Imports: ggplot2, ggrepel, gridExtra, chron, xml2, dplyr (≥ 0.8.5), tibble, gghalves, ggdist
Suggests: testthat, knitr, rmarkdown
Published: 2022-04-06
Author: Justin Wilkins ORCID iD [aut, cre], Bill Denney ORCID iD [aut], Rik Schoemaker [aut], Satyaprakash Nayak [ctb], Leonid Gibiansky [ctb], Andrew Hooker [ctb], E. Niclas Jonsson [ctb], Mats O. Karlsson [ctb], John Johnson [ctb]
Maintainer: Justin Wilkins <justin.wilkins at occams.com>
Contact: Justin Wilkins <justin.wilkins@occams.com>
BugReports: https://github.com/kestrel99/pmxTools/issues
License: GPL-2
URL: https://github.com/kestrel99/pmxTools
NeedsCompilation: no
Materials: README NEWS
In views: Pharmacokinetics
CRAN checks: pmxTools results

Documentation:

Reference manual: pmxTools.pdf
Vignettes: Drawing PK curves with pmxTools

Downloads:

Package source: pmxTools_1.2.3.tar.gz
Windows binaries: r-devel: pmxTools_1.2.3.zip, r-release: pmxTools_1.2.3.zip, r-oldrel: pmxTools_1.2.3.zip
macOS binaries: r-release (arm64): pmxTools_1.2.3.tgz, r-oldrel (arm64): pmxTools_1.2.3.tgz, r-release (x86_64): pmxTools_1.2.3.tgz, r-oldrel (x86_64): pmxTools_1.2.3.tgz
Old sources: pmxTools archive

Reverse dependencies:

Reverse suggests: mrgsolve, NMproject

Linking:

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