rescue: Bootstrap Imputation for Single-Cell RNA-Seq Data

Given a log-transformed expression matrix and list of informative genes: subsample informative genes, cluster samples using shared nearest neighbors clustering, estimate missing expression values with the distribution mean of means extrapolated from these cell clusterings, and return an imputed expression matrix. See Tracy, S., Yuan, G.C. and Dries, R. (2019) <doi:10.1186/s12859-019-2977-0> for more details.

Version: 1.0.3
Depends: R (≥ 3.4.0), utils
Imports: data.table, dbscan (≥ 1.1-3), igraph (≥ 1.2.4.1), irlba, Matrix, methods, parallel, reticulate (≥ 1.14)
Suggests: knitr, rmarkdown
Published: 2020-07-18
Author: Sam Tracy & Ruben Dries
Maintainer: Sam Tracy <seasamgo at gmail.com>
BugReports: http://github.com/seasamgo/rescue/issues
License: GPL-2 | GPL-3
URL: https://github.com/seasamgo/rescue
NeedsCompilation: no
CRAN checks: rescue results

Documentation:

Reference manual: rescue.pdf

Downloads:

Package source: rescue_1.0.3.tar.gz
Windows binaries: r-devel: rescue_1.0.3.zip, r-release: rescue_1.0.3.zip, r-oldrel: rescue_1.0.3.zip
macOS binaries: r-release (arm64): rescue_1.0.3.tgz, r-oldrel (arm64): rescue_1.0.3.tgz, r-release (x86_64): rescue_1.0.3.tgz, r-oldrel (x86_64): rescue_1.0.3.tgz

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