Tipping point analysis for clinical trials that employ Bayesian dynamic borrowing via robust meta-analytic predictive (MAP) priors. Mainly an implementation of an approach proposed by Best and colleagues (2021) is provided <doi:10.1002/pst.2093>. Intended use is the planning, analysis and interpretation of extrapolation studies in pediatric drug development, but applicability is generally wider.
Version: | 0.1.7 |
Depends: | R (≥ 3.5.0) |
Imports: | dplyr, ggplot2, RBesT |
Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
Published: | 2022-07-12 |
Author: | Morten Dreher [aut], Christian Stock [aut, cre] |
Maintainer: | Christian Stock <christian.stock at boehringer-ingelheim.com> |
License: | GPL (≥ 3) |
NeedsCompilation: | no |
Materials: | README NEWS |
CRAN checks: | tipmap results |
Reference manual: | tipmap.pdf |
Package source: | tipmap_0.1.7.tar.gz |
Windows binaries: | r-devel: tipmap_0.1.7.zip, r-release: tipmap_0.1.7.zip, r-oldrel: tipmap_0.1.7.zip |
macOS binaries: | r-release (arm64): tipmap_0.1.7.tgz, r-oldrel (arm64): tipmap_0.1.7.tgz, r-release (x86_64): tipmap_0.1.7.tgz, r-oldrel (x86_64): tipmap_0.1.7.tgz |
Old sources: | tipmap archive |
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