Subgroup Specific Optimal Dose Assignment


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Documentation for package ‘SubTite’ version 3.0.1

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GetESS Determines Prior ESS for fixed values of sigma_alpha^2 and sigmabeta^2
GetParams Obtains true simulation parameters for each supported distribution function to correspond to a probability of the truth by time T1.
GetPriorMeans Calibrates prior means for Dose Finding Trial
GetSubTite Gives the subgroup specific optimal dose vector. Returns a list containing the optimal doses to enroll each subgroup at and the subgroups that should have their accrual suspended temporarily.
MCMC Performs MCMC and returns needed values for dose-finding in a list.
MCMCSIM Performs MCMC and returns needed values for dose-finding in a list.
SimTrial Simulates a Sub-TITE trial design
SimTrial1 Simulates a Sub-TITE trial design