Randomization for Clinical Trials


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Documentation for package ‘randomizeR’ version 1.4.2

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A B C D E G H I K L M N O P R S T U misc

randomizeR-package Randomization for Clinical Trials

-- A --

a Function returning the adjusting parameter a slot of an S4 object
abcdPar Representing Accelerated Biased Coin Design
abcdRand Sampling algorithm for abcd
assess Assessing randomization sequences
assess-method Assessing randomization sequences

-- B --

bbcdPar Representing Bayesian Biased Coin Design
bbcdRand Sampling algorithm for bbcd
blocks Function returning the block slot of an S4 object
bsdPar Representing Big Stick Design
bsdRand Sampling algorithm for BSD

-- C --

calcProb Theoretical probability for randomization sequences
calculateProbabilities Theoretical probability for randomization sequences
chenPar Representing Chen's Design
chenRand Representing Chen's Design
chronBias Representing chronological bias
coin Function returning the coin slot of an S4 object
combineBias Combined additive bias criterion
compare Comparison of randomization procedures
compare-method Comparison of randomization procedures
corGuess Representing the expected number of correct guesses
createParam Representing any randomization procedure
createSeq Query to create a randomization sequence of a particular randomization procedure
crPar Representing Complete Randomization

-- D --

derFunc Representing Derringer-Suich desirability functions
derFunc-class Parameters generic
desirability Desirability functions within the scope of clinical trials
doublyF_opt Distribution function of the non central F-distribution
doublyF_value Rejection probability for one sequence in the presence of selection bias
doublyF_values Rejection probability in case of selection bias in multi-arm trials
doublyT Approximation of the distribution function of the doubly noncentral t-distribution
doublyTValues Calculation of the biased type-one-error (resp. power) of Student's t-test

-- E --

ebcPar Representing Efron's Biased Coin Design
evaluate Evaluation of several randomization procedures with respect to certain desirability functions applied to specified issues.
evaluate-method Evaluation of several randomization procedures with respect to certain desirability functions applied to specified issues.

-- G --

gbcdPar Representing Generalized Biased Coin Design
gbcdRand Sampling algorithm for gbcd
generateAllSequences Complete set of randomization sequences
generateRandomSequences Generate random sequences
genNcps Calculation of the NCPs of each randomization sequence for the doubly noncentral t-distribution
genSeq Generate random sequences
genSeq-method Generate random sequences
getAllSeq Complete set of randomization sequences
getAllSeq-method Complete set of randomization sequences
getbiasCS1 Biasing Policy for a Group of Favoured Treatments
getbiasCS2 Biasing Policy for Avoiding the Placebo Treatment
getCorGuesses Matrix of the guesses of the investigator
getDesFunc Type of Desirability function
getDesFunc-method Type of Desirability function
getDesign Design of a randomization procedure
getDesign-method Design of a randomization procedure
getDesScores Applying desirability functions on issues of individual randomization sequences
getDesScores-method Applying desirability functions on issues of individual randomization sequences
getExpectation Get expectations of a randomization list
getExpectation-method Get expectations of a randomization list
getProb Theoretical probability for randomization sequences
getProb-method Theoretical probability for randomization sequences
getProbabilities Theoretical probability for randomization sequences
getRandList Accessor function for the randomization list
getRandomizationList Accessor function for the randomization list

-- H --

hadaPar Representing Hadamard Randomization
hasAllGroups Check function for occurance of all treatment groups in the sequence
hatMatrix Calculate hat matrix

-- I --

imbal Representing the allocation imbalance
issue Assessment criteria for clinical trials
issues Assessment criteria for clinical trials

-- K --

K Function returning the total sample size slot of an S4 object

-- L --

lambda1 Calculate first non centrality parameter of the doubly non central F-distribution
lambda2 Calculate second non centrality parameter of the doubly non central F-distribution

-- M --

makeBiasedExpectation Calculate Expectation vector
makeDesignMatrix Design Matrix
method Function returning the allocation ratio slot of an S4 object
mpPar Representing Maximal Procedure
mti Function returning the MTI slot of an S4 object
mu Access the expectation value slot of a normEndp S4 object

-- N --

N Function returning the sample size slot of an S4 object
normEndp Representation of normally distributed endpoints

-- O --

overview Overview over the parameters used in the 'randomizeR' package

-- P --

pbrPar Representing Permuted Block Randomization
plot Generic plotting of comparison objects
plot-method Generic plotting of comparison objects
plotDes desScore plotting
plotEv Evaluation plotting
plotSeq Sequence plotting
probUnDes Computing the probability of having desirabilty scores of zero
probUnDes-method Computing the probability of having desirabilty scores of zero

-- R --

randBlocks Function returning the block slot of an S4 object
randomizeR Randomization for Clinical Trials
randPar Settings for randomization procedures
randPar-class Randomization paramters
randSeq-class An S4 Class for the representation of randomization sequences
rarPar Representing Random Allocation Rule
ratio Function returning the allocation ratio slot of an S4 object
rho Function returning the adjusting parameter rho slot of an S4 object
rpbrPar Representing Randomized Permuted Block Randomization
rtbdPar Representing Randomized Truncated Binomial Design

-- S --

saveAssess Saving an assess object
saveRand Saving a randomization lists
seed Function returning the allocation seed slot of an object
selBias Representing selection bias
setPower Representing the power
sigma Function returning the standard deviation slot of a normEndp S4 object
summary Summary of assessments of a randomization procedure
summary-method Summary of assessments of a randomization procedure

-- T --

tbdPar Representing Truncated Binomal Design
TV Function returning the sample size slot of an S4 object
type Get type of an object

-- U --

udPar Representing Wei's Urn Design

-- misc --

$-method Method defining the $ operator for the assessemnt class
$-method Method defining the $ operator for the assessemnt class
$-method Method defining the $ operator for the derFunc class
$-method Method defining the $ operator for the desFunc class
$-method Method defining the $ operator for the assessemnt class
$-method Method defining the $ operator for the endpoint class
$-method Method defining the $ operator for the evaluation class
$-method Method defining the $ operator for the issue class
$-method Method defining the $ operator for the probUnDesirable class
$-method Method defining the $ operator for the randPar class
$-method Method defining the $ operator for the randSeq class