Escalation with Overdose Control


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Documentation for package ‘ewoc’ version 0.2.0

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accuracy_index Accuracy Index
average_toxicity Average Toxicity Number
dlt_rate Evaluation of the DLT rate
ewoc_d1classic Escalation With Overdose Control
ewoc_d1extended Escalation With Overdose Control
ewoc_d1ph Escalation With Overdose Control
ewoc_simulation Generic EWOC simulation
inv_standard_dose Inverse standardization of the dose
logit Logit
mtd_bias Bias of the MTD estimates
mtd_mse Mean Square Error of the MTD estimates
optimal_mtd Percent of doses in relation the optimal MTD interval
optimal_toxicity Percent of doses in relation the optimal toxicity interval
pdlt_d1classic Generating a probability of DLT function based on the EWOC classic model
pdlt_d1extended Generating a probability of DLT function based on the EWOC extended model
pdlt_d1ph Generating a probability of DLT function based on the EWOC Proportional Hazards model
response_d1classic Generating a binary response function based on the EWOC classic model
response_d1extended Generating a binary response function based on the EWOC extended model
response_d1ph Generating a response function based on the EWOC Proportional Hazards model
standard_dose Standardization of the dose
stop_rule Evaluation of the stop rule
stop_rule_sim Generating a stop rule function