* using log directory 'd:/Rcompile/CRANpkg/local/4.1/cRegulome.Rcheck'
* using R version 4.1.3 (2022-03-10)
* using platform: x86_64-w64-mingw32 (64-bit)
* using session charset: ISO8859-1
* checking for file 'cRegulome/DESCRIPTION' ... OK
* checking extension type ... Package
* this is package 'cRegulome' version '0.3.2'
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking whether package 'cRegulome' can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking 'build' directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
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* checking loading without being on the library search path ... OK
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* checking R code for possible problems ... [9s] OK
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* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
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* checking for unstated dependencies in examples ... OK
* checking LazyData ... NOTE
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* checking installed files from 'inst/doc' ... OK
* checking files in 'vignettes' ... OK
* checking examples ... [9s] OK
* checking for unstated dependencies in 'tests' ... OK
* checking tests ... [12s] OK
  Running 'testthat.R' [12s]
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in 'inst/doc' ... OK
* checking re-building of vignette outputs ... [30s] WARNING
Error(s) in re-building vignettes:
--- re-building 'case_study.Rmd' using rmarkdown
Loading required package: R.oo
Loading required package: R.methodsS3
R.methodsS3 v1.8.2 (2022-06-13 22:00:14 UTC) successfully loaded. See ?R.methodsS3 for help.
R.oo v1.25.0 (2022-06-12 02:20:02 UTC) successfully loaded. See ?R.oo for help.

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R.utils v2.12.0 (2022-06-28 03:20:05 UTC) successfully loaded. See ?R.utils for help.

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Loading required package: Biobase
Welcome to Bioconductor

    Vignettes contain introductory material; view with
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clusterProfiler v4.2.2  For help: https://yulab-smu.top/biomedical-knowledge-mining-book/

If you use clusterProfiler in published research, please cite:
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu. clusterProfiler 4.0: A universal enrichment tool for interpreting omics data. The Innovation. 2021, 2(3):100141

Attaching package: 'clusterProfiler'

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trying URL 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393113/bin/pone.0122882.s001.xlsx'
Warning in download.file("https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393113/bin/pone.0122882.s001.xlsx",  :
  InternetOpenUrl failed: 'Die Serververbindung konnte nicht hergestellt werden.'
Quitting from lines 44-55 (case_study.Rmd) 
Error: processing vignette 'case_study.Rmd' failed with diagnostics:
cannot open URL 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393113/bin/pone.0122882.s001.xlsx'
--- failed re-building 'case_study.Rmd'

--- re-building 'using_cRegulome.Rmd' using rmarkdown
Picking joint bandwidth of 0.0445
--- finished re-building 'using_cRegulome.Rmd'

SUMMARY: processing the following file failed:
  'case_study.Rmd'

Error: Vignette re-building failed.
Execution halted

* checking PDF version of manual ... OK
* DONE
Status: 1 WARNING, 1 NOTE