dnapath: Differential Network Analysis using Gene Pathways

Integrates pathway information into the differential network analysis of two gene expression datasets as described in Grimes, Potter, and Datta (2019) <doi:10.1038/s41598-019-41918-3>. Provides summary functions to break down the results at the pathway, gene, or individual connection level. The differential networks for each pathway of interest can be plotted, and the visualization will highlight any differentially expressed genes and all of the gene-gene associations that are significantly differentially connected.

Version: 0.7.4
Depends: R (≥ 3.6)
Imports: Rcpp (≥ 1.0.1), corpcor, igraph, ggplot2, SeqNet, Rdpack, dplyr, tibble, stats, methods, curl, graphics, grDevices, gtools, utils, wCorr, parallel
LinkingTo: Rcpp, RcppArmadillo
Suggests: testthat (≥ 2.1.0), knitr, rmarkdown, markdown, xml2, readr, bc3net, DWLasso, huge, GENIE3, minet, AnnotationDbi, reactome.db, biomaRt
Published: 2022-05-09
Author: Tyler Grimes [aut, cre], Somnath Datta [aut]
Maintainer: Tyler Grimes <tyler.grimes at unf.edu>
License: GPL-2 | GPL-3
NeedsCompilation: yes
SystemRequirements: C++11
Citation: dnapath citation info
CRAN checks: dnapath results

Documentation:

Reference manual: dnapath.pdf
Vignettes: Introduction to dnapath
Package datasets

Downloads:

Package source: dnapath_0.7.4.tar.gz
Windows binaries: r-devel: dnapath_0.7.4.zip, r-release: dnapath_0.7.4.zip, r-oldrel: dnapath_0.7.4.zip
macOS binaries: r-release (arm64): dnapath_0.7.4.tgz, r-oldrel (arm64): dnapath_0.7.4.tgz, r-release (x86_64): dnapath_0.7.4.tgz, r-oldrel (x86_64): dnapath_0.7.4.tgz
Old sources: dnapath archive

Linking:

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