Fit and compare nonlinear mixed-effects models in
differential equations with flexible dosing information commonly seen
in pharmacokinetics and pharmacodynamics (Almquist, Leander, and
Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation
solving is by compiled C code provided in the 'rxode2' package (Wang,
Hallow, and James 2015 <doi:10.1002/psp4.12052>).
| Version: |
2.0.8 |
| Depends: |
nlmixr2data, R (≥ 4.0) |
| Imports: |
backports, checkmate, cli, graphics, knitr, lbfgsb3c, lotri, magrittr, Matrix, methods, minqa, n1qn1 (≥ 6.0.1-10), nlme, Rcpp, rex, Rvmmin, rxode2 (≥ 2.0.7), stats, symengine, ucminf, utils, vpc |
| LinkingTo: |
BH, dparser (≥ 0.1.8), lbfgsb3c, Rcpp, RcppArmadillo (≥
0.5.600.2.0), RcppEigen (≥ 0.3.3.3.0), rxode2 (≥ 2.0.7), StanHeaders (≥ 2.18.0) |
| Suggests: |
broom.mixed, crayon, data.table, devtools, digest, dparser (≥ 0.1.8), dplyr, generics, nloptr, qs, sys, testthat, tibble, withr, xgxr |
| Published: |
2022-06-22 |
| Author: |
Matthew Fidler 
[aut, cre],
Yuan Xiong [aut],
Rik Schoemaker
[aut],
Justin Wilkins
[aut],
Wenping Wang [aut],
Robert Leary [ctb],
Mason McComb
[ctb],
Vipul Mann [aut],
Mirjam Trame [ctb],
Mahmoud Abdelwahab [ctb],
Teun Post [ctb],
Richard Hooijmaijers [aut],
Hadley Wickham [ctb],
Dirk Eddelbuettel [cph],
Johannes Pfeifer [ctb],
Robert B. Schnabel [ctb],
Elizabeth Eskow [ctb],
Emmanuelle Comets [ctb],
Audrey Lavenu [ctb],
Marc Lavielle [ctb],
David Ardia [cph],
Katharine Mullen [cph],
Ben Goodrich [ctb] |
| Maintainer: |
Matthew Fidler <matthew.fidler at gmail.com> |
| License: |
GPL (≥ 3) |
| URL: |
https://github.com/nlmixr2/nlmixr2est |
| NeedsCompilation: |
yes |
| Language: |
en-US |
| Citation: |
nlmixr2est citation info |
| Materials: |
NEWS |
| CRAN checks: |
nlmixr2est results |